The At-risk Youths in the United States

In the United states of America there are some factors that prone to affecting the youths, and this is because of there state in human development, which is provided by nature.The youths normally engage in varied activities at their youth stage in trying to understand the ideologies behind the various concepts of life in them satisfying their curiosity. Some of this actives are likely either to benefit them or certain to make their lives horrible. At the youth stage, the youths can be perceived to be persons whose rationality have not full developed in them identifying what is good of them because of less live experiences and most serious factor is their inability to resist to the peer influences which might be either positive or   negative.The youths in their adventure to satisfy curiosity they normally find themselves in the traps of teen pregnancies, substance abuse, delinquency and criminal activities. It can happen that it was not their wish to have   found themselves in thi s situation but its due to the anxiety in them in trying to venture and discover the real life which they have been hearing the elderly talking about.The traps in which they find themselves in , which can also be perceived as social evils can be solved if these youths find a good guide on what is expected of them, and more especially to make them occupied in constructive activities which are certain to mould their livelihood at the current state and in the future.Lack of proper guidance and influencing facilities is what sways them into such traps of life given that their rationality have not full developed, thus a need for them to be provided with the necessary information in them making informed choices.This paper is addressing   the four main traps in which the United States of America youth fall into, and they include substance abuse, teen pregnancies, delinquency, and   criminal activities. The paper treats these traps as being caused by certain acquired traits, and where t he traits acquired depends the kind of environment in which the youths resides, the ability of their parents to guide them, the kind of peers they spend time with, access to various social facilities and also at some level economic status of the families where this youths belong.Delinquency is a terminology which is used to explain the behavior of the children and the adolescents that is likely to be judged in the criminal law among the adults. The age for the crime to be grouped under delinquency normally vary from one state to other and   the age limit vary from 14 years to 21 years in some states, although the some states the the age group 16-20 years is considered as adults in some states.The age group of 16-21 is perceives to be the age group which the worst delinquency crimes, where theft is the most committed crime. Rape is common in the late adolescent age. The reasons that lead to the youths   into such crimes can be explained by the varied psychological, social and eco nomic factors. A number of researchers have been carried on about the factor where most of them have associated it to issues like the disorganized family situations and also the economic status of the neighbourhood.(http://encyclopedia2.thefreedictionary.com/Juvenile+Deliquency   )   The crimes associated with delinquency in the United states are common the inner cities. the decision to treat delinquency crimes separately compared to the adult crimes was implemented in 1899, where is advocated for informal procedures and correction other than handling it like a punishment for the crime committed, and mostly involves handling delinquency crimes in juvenile correction institutions in moulding them to change their behavior to make them potential future responsible citizens of the United states. In this juvenile correction institutions there are established rehabilitation programs that both provided vocational training and also psychiatric treatments.Substance abuse is also another trap in which a large number of the youth fall into, where it is estimated that almost 8.6 million youths ages between 12 to 17   abuse substances, which is one third of the United States age group, as per to the date realised by the Substance Abuse and Mental Health Administration in 2007.More than 650,000 youths normally engage in alcohol use, and a number of at least 9 million also engage in delinquent behavior within this age group (http://alcoholism.about.com/od/teens/a/blsam050404.htm ). The data from the Alcohol use and   delinquency Behaviors among the youths shows that there is a very high correlation between the delinquency participation   and also the participation in substance abuse, as the very youths who engage in substance abuse normally find themselves in delinquent activities and most likely because of the drive that they get from the alcohol influence.The substance abuse is a serious problem that has to be addressed as noted by the Substance Abuse   and men tal health administration Administrator, Charles Curie, in him commenting that heavy alcohol use among the youths is not just illegal but also a cause to fighting, stealing, selling drugs and the carrying of the handgun, where in this case heavy alcohol means taking more than five drinks in a single sitting for more than five time in the past thirty days (http://alcoholism.about.com/od/news/a/nasd2005.htm ).The teen pregnancies has also been an issue among the United States youths that draws attention for its address. The has has been a decline in the teenage pregnancies, abortion and also child birth among the youths since 1991, and this is attributed to the reason that youth have been in the recent past frequent users of contraceptives, and also many have opted to abstain from sex during their middle and early adolescence. This change have been experiences across all the races of the United States.The Teenage have been declining across the years in every state including the Distri cts of Colombia and also the Virgin lands. Despite the good news of declining youth teen pregnancies, the United states still remain to lead in the youth pregnancy cases among the industrialised nations, which implies that it has not got into full control of the situation compared to the industrialized nations.The ages of 18 and 19 years are the ones which are prone to teenage pregnancies other than any other age groups in the United states, which accounts for 66 percent   of the United states teen births, where most teenage mothers normally ail from socially and economically disadvantaged family background, thus being caught within the consequences of this traps (http://www.advocatesforyouth.org/teenpregnancy.htm ).Therefore the youth pregnancy is an issue to be addressed within the national scope at it also has adverse effects in making the youths quite irresponsible citizens given that their abilities are never discovered and exploited due to diverted attentions which destruct them from achieving   future set goals, thus an important issue to address.

Exercise during pregnancy Essay

Pregnancy brings along a number of physiological, emotional and psychological changes for expectant mothers. Researchers, though they usually disagree on the intensity and type of physical activity or exercise that pregnant women should be involved in, agree that some form of exercise is useful for pregnant women. Poudevigne and O’Connor (2006) discuss several research which highlight the psychological problems that some pregnant women face and the challenges in dealing with them (4). Smith and Michel (2006) sought to determine the effect an aquatic exercise program would have on the pregnant mother. The researchers wanted to find out if participant’s would be more willing to participate in health-promoting activities and if there would be any improvement to physical discomfort and mobility problems (5) as a result of the aquatic exercise program. Forty non-exercising pregnant women who were at least 19 weeks pregnant were recruited. Participants opted to be in either the experimental or control group with each having 20 members. Over a six-week period the 20 members of the experimental group were involved in three weekly 60 minute sessions of aquatic exercise. The members of the control group were instructed to continue their usual non-exercising routine (5). The researchers did pre-and post-test comparisons as well as comparisons between the results of both control and experimental group. The results from these comparisons supported the researchers’ hypotheses that exposure to the exercise program would have a positive impact on participants’ involvement in other health-promoting activities. Similarly it was found that those involved in the exercise program experienced less physical discomfort and demonstrated improvements in their mobility and perceptions of their body image (5). I believe the findings reported by Poudevigne and O’Connor (2006) are quite useful for pregnant mothers who want to exercise but are worried about the type of exercises to perform. It appears that the aquatic exercises would be a welcome alternative to women than regular gym-type and strenuous exercises. It would be good if future research compared the effectiveness of these two types of exercises. Some researchers are not convinced that exercise alone can accomplish physical improvements for mothers, particularly during the advanced pregnancy stage. Depledge, McNair, Keal-Smith and Williams (2005) hypothesized that exercise with other supports could improve physical conditions. The research objective was to see if the conditions of pregnant women with symphysis pubis dysfunction, or pelvic joint pain, would improve with exercise and interventions such as advice and pelvic support belts. The researchers felt this study was essential given the increase in the number of pregnant women experiencing this condition. Methods that would diminish pelvic discomfort in pregnant women would therefore be quite useful in improving how well this condition is dealt with both by clinicians and the expectant mothers themselves (1). The participants in the research were randomly assigned to one of three groups. There was an exercise only group along with advice, a group that combined exercise with wearing a non-rigid support belt and the third group combined exercise with a rigid support belt. Participants were divided into each group relatively evenly – 30, 28 and 29 respectively. The intervention program lasted for a week and pre- and post- test analysis of level of discomfort and intensity of pelvic pain were recorded (1). The results of the research revealed that all three groups reported some amount of improvement in their pelvic pain over the period. However the variation between groups was not very significant (1). I found the results of this research to be particularly interesting since it suggests that the use of support belts does not result in any additional improvements over exercise. This demonstrates the extent to which exercise can improve the conditions of pregnant women, even those with considerable levels of pelvic pain due to symphsis pubis dysfunction. Often some mothers desiring to participate in exercise are confused by physician’s reports which suggest that exercise is unsafe for the expectant mothers because of the risk of maternal hypothermia (2) and an untimely or late delivery (3). In fact Poudevigne and O’Connor (2006) did a comprehensive review of research on the subject and discovered that a significant number of women, who were physically active before their pregnancy, demonstrated a decrease in these activities throughout their pregnancy (4). Larsson & Lindqvist (2005) tested the merits of this position in a study of 37 pregnant women participating in low-impact exercises (2). They discovered little risk to the pregnant women who revealed comparable core temperature, heart rate and oxygen saturation as compared to a control of 11. This suggests therefore, that the participants and, by extension, pregnant mothers at whatever stage of pregnancy, are at little risk of maternal hypothermia doing low-impact exercises (2). Similarly Leiferman and Evenson (2003) report in their study of close to 10, 000 mothers, that there was little or no risk that mothers would deliver their babies either pre- or post- term as the skeptics of exercise during pregnancy usually suggest (3). This information I find relieving for mothers who are concerned about the welfare of the fetus during exercise. Since there is little risk with low-impact exercises pregnant mothers should no longer have significant objections to exercise. Evidently research supports the view that exercise during pregnancy is harmful neither to the mother nor the unborn fetus. Exercise seems to be beneficial in relieving some of the discomforts faced by expecting mothers both of the physical and psychological nature. While there is no suggestion that exercise offers much further benefits over other interventions or a sedentary lifestyle, it has not been shown to be harmful.

Marketing Research - SPSS analysis Essay Example | Topics and Well Written Essays - 750 words

Marketing Research - SPSS analysis - Essay Example The frequency chart below shows that the shopping mall is the most preferred shopping destination of all the respondents. Given below is the correlation between the shopping destination preferences of the respondents. We find that there is significant negative correlation between high end department stores and the other variables showing that the respondents significantly prefer high end department stores than others. We find that 39 of the respondents do not use television as the source of information. The Fisher’s exact test shows that there exists no significant difference between the male and female with regard to this source. We find that 42 of the respondents use magazine as the source of information. Only 6 of the 36 females do not use magazine as a source. The Fisher’s exact test shows that there exists significant difference between the male and female with regard to this source. All other sources involved in the study are also used by the respondents as sources of information but do not produce significant results of difference between male and female. We also realize that the radio is not used as a source of information by all the respondents. We find that there exists significant correlation between the respondents’ likeliness to purchase underwear and formal top. Similarly there exists significant correlation between the likeliness to purchase skirt/trousers and shirt blouse. There exists no significant negative correlation between the various aspects of

How and why did European states abandon or redefine their empires in Essay

How and why did European states abandon or redefine their empires in the 1950s and 1960s - Essay Example 15). In 1956 France passed laws that allowed elected officials in colonies to decide labor legislation. The French would continue to give sovereignty to these colonies until France many colonies in Africa their independence in 1960, and then Algeria at the end of the Algerian War in 1962. The case was different in colonial Sudan under Britain. America once supported British imperialism. However, according to White by the 1950’ the Americans came "to view controlled decolonisation as an essential element in Cold War strategy; the continuance of European imperialism would only drive nationalist movements into the arms of the Soviet Union" (p. 68). After the United States withdrew its promise to help construct the Aswan Dam due to Egypt’s increasing relationship with the U.S.S.R. the Egyptian president nationalized the canal, leading to the Suez Crisis. After the crisis and America failing to step in and aiding its allies, the U.S.S.R. accused the West as being weak and di vided. Several colonies in Africa, including the British colony Anglo-Sudan gained their independence in the following years.

Single Parenting Essay Example | Topics and Well Written Essays - 2500 words

Single Parenting - Essay Example This situation can be reached with divorce, separation or break up after the relation without marriage. Though single parent families started originating in the early 1950's, they were at their peak somewhere around the late 1980's and 1990's. The main cause of a complete family being broken down into a single parent family was the death of a partner. However, the trend changed, and the main cause turned towards the divorce between partners. It is this addition of several new causes, especially divorce, that the single parent family form is the fastest growing form of family in the North America. The first surprising fact about single parenting is that this phenomenon has been defined in two different ways. The following definition of single parents is distinct by only a single feature. Single parenting is a situation where the sole parent is responsible for the upbringing of the child. The sole parent does not receive any form of assistance from the other parent due to circumstances such as death, abandonment, etc. There can be several other reasons beside a few listed. According to this definition, some single parents might not be entitled to hold the status of being a single parent. However, as discussed earlier, the changing trend brought with it, changes in the causes of becoming a single parent. ... However, the second half of this decade saw a general decline in the rise of single parent families. The rise of single parent families that dominated the US culture for 4 decades, ended 1996 onwards (Statistics). Reports in 1960 suggested that only 9 percent of the total children’s' population in the US was living in single parent families. This rose to a staggering 25% in 1990 and to 28% in the year 2000 (Simmons and ’Neill). It is interesting to note how these changes came about in statistical terms. Three separate trends of the family culture can be identified. Between 1996 – 2000, the share of children living with a never married parent rose to 11.0 percent from 10.6 percent. However, this first trend was offset by the second trend. The percentage of children living with a divorced parent dropped to 15.6 percent from 17.3 percent. The third trend, children living with a widowed parent, maintained a constant percentage of 1.2 percent. These figures depict tha t the number of children living with a never married parent increased by 400,000 whereas the number of children living with a divorced parent decreased by 1 million (Statistics). The US Census from the year 2000 shows us that 12.2% of all households are female single parent households whereas 4.2% of all households are male single parent households. According to these statistics there are a total number of 17,294,115 single parent families in the US alone (Weiss). The trend in the United Kingdom has been similar. Over a quarter (26%) of the families in Britain are single parent families. In numbers, there are over 2 million parents in Britain today, though this number has remained more or less constant since the

Bacteriocins and Their Impact on Our Lives and Agriculture Article

Bacteriocins and Their Impact on Our Lives and Agriculture - Article Example Andre Gratia was the first to uncover the inhibition property of bacteriocins in a compound he named colicin v, which was released by a virulent strain of E.coli bacteria. In 1954, Pierre Frederic uncovered the genetic determinates of colicin, as a conjugation transmissible element that is similar to the F factor. Since then a host of bacteriocins have been discovered, and our understanding of the usefulness of bacteriocins moves forward (Scienceray, 2012). Bacteriocins Bacteriocins are a constituent of the wide array of microbial defense systems. All bacteria produce bacteriocins (Riley & Chavan, 2007). These bacteriocins are proteinaceous compounds, which are lethal to bacteria other than the releasing strain. The spectrum of antibacterial activity can vary from narrow spectrum, with confined inhibition of closely related bacterial species or broad to include several of the other bacterial species (Joerger, 2003). Bacteriocins from gram positive bacteria are associated with the bro ader range of antibacterial range of activity. While initial studies were focused on colicins from E-coli and the bacteriocins from other gram negative bacteria, the current focus of studies on bacteriocins is on the bacteriocins from the gram positive bacteria, as they are assumed to have more application in humans and in foods and other products (Chen & Hoover, 2003). At first glance there may be a tendency to classify the bacteriocins as an extension of the traditional peptide antibiotics, because they are synthesized peptides. Yet, they are different, and it is in the essence of this difference that their utility lies. Unlike peptide antibiotics, which are synthesized by enzymes bacteriocins are ribosomally synthesized peptides. In addition, while typical antibiotics are active against a broad range of bacteria, bacteriocins have a narrow range of activity within its own bacteria species or closely related bacteria species. Furthermore, there is an important and unique differenc e in the potency. Within its narrow range of antibacterial activity it is potent in nanomolar concentrations, while in the case of antibiotics a much higher concentration is required for potent antibiotic activity. Though the initial origins and studies on bacteriocins pertain to those produced by gram negative bacteria, the current research on bacteriocins focuses more on the bacteriocins produced by gram positive bacteria, because of the greater potential utility seen in them. Any evaluation of bacteriocins produced by gram positive bacteria is best undertaken by studying them as two groups, namely the heat-stable lantibiotics and the nonmodified heat-stable bacteriocins (Nes, 2011). Bacteriocins from the gram positive lactobacillus are the most investigated group of bacteriocins. Class – I of these bacteriocins consist of the lantibiotics, which are heat stable. They comprise of post-transitionally modified peptides, having multiple rings, bridged by lanthiones or methylla nthionine residues (Zendo & Sonomoto, 2011). Class I bacteriocins are further

Denver art museum Essay Example | Topics and Well Written Essays - 500 words - 5

Denver art museum - Essay Example It appears, after some time observing it, to be a functional piece of furniture, very chic and flirtatious. The concept and design is simple, but whimsical. It appeared to be made of patent leather or similar material, and it comes in a variety of colors to suit any dà ©cor. This is a very quirky piece, I found it very appealing. The tipi of Standing Bear was very moving to see. It brought feelings of remorse as well as excitement to see such an incredible piece of American history. Given what the white man did to the Indian people, seeing this tipi was and emotional experience. It depicted many horses being ridden as well as herded; perhaps symbolizing the horses Standing Bear took from other tribes. It is a very colorful, beautiful piece that should be regarded with tranquility. â€Å"Dylan†, by Milton Glaser (1966) is definitely apiece appropriate for its time. The colors are vibrant and attracting, reminiscent of the turbulence of the ‘60’s. It portrayed, at least to me, the mix of thought and feelings of that period, and the inner struggles that people had to endure at the time. It is a stunning piece that moves the soul. Hock E Aye Vi Edgar’s â€Å"Heap of Birds† (2004), is simply extraordinary. Its subtle tone leaves the soul feeling pitiful. The trees that he created feel more like tombstones or crosses instead of actual trees. He consciously references indigenous people and their cultures in each tree. The wheel that the trees become represent to me a changing of the tides of the world, culturally, spiritually and economically. It just leaves the heart crying, needing redemption. This is a superb piece that is extremely difficult to take your eye from it is so moving. â€Å"Venturi Faà §ade†, by Rauch, Brown and Venturi (1979) just shrieks 1970’s pop culture. The flowers are unlike any other period of art, loud, vivacious and huge. They used muted tones with a splash of

JavaScript Essay Example | Topics and Well Written Essays - 1000 words

JavaScript - Essay Example In the course of its development however, it has gone beyond the realm of simple interactive web features to become a â€Å"respected programming language used by corporations and developers across the globe to make incredible applications† (Resig, 2006, p. 3). JavaScript 2.0, the next major release, is currently under development. The success of any scripting language lies in its compatibility across different browsers, operating systems and platforms. A language developed by Netscape and Mozilla Foundation, JavaScript is naturally fully supported on all Netscape and Mozilla browsers (Lemay, 1996, p. 8). Increasing popularity however pushed other web browsers to support the language or implement a dialect that is compatible with ECMAScript. ECMAScript is yet another scripting language developed by Ecma International; according to a Wikipedia (2009) article, JavaScript is in fact just a dialect of ECMAScript. In this section, we shall examine whether JavaScript is a truly cross-platform application. We shall begin by checking popular browsers for JavaScript support. Netscape Navigator and Mozilla Firefox are, as mentioned, out of the question, leaving us only with Internet Explorer, Safari, Google Chrome and Opera. Internet Explorer. JScript, an ECMAScript dialect, is Microsoft’s answer to JavaScript’s popularity. Because JScript and JavaScript are derived from ECMAScript, the two have minor differences. In other words, an IE browser may, to some extent, read a code differently from a Firefox browser. Thankfully, McFedries (2001) confirms that these differences are trivial and that commonly used JavaScript codes will still run smoothly on non-Mozilla or non-Netscape browsers. Safari. About two years ago, Safari, a browser developed by Apple, was made available to Windows. Luckily, â€Å"Safari uses Apples WebKit for rendering web pages and running JavaScript†, as stated in a Wikipedia

About photo Essay Example | Topics and Well Written Essays - 500 words - 1

About photo - Essay Example Police officers have been quoting Section 44 of Terrorism Act 2000 when arresting photographers for photographing certain public places terming the act as being illegal. However, this paper aims at making the readers know that the power of law enforcement officers to stop and search photographers doing public photographing was ruled illegal during the year 2010. Therefore, photographers have the right to take photographs of public places in which they have legal access to without being stopped, searched or arrested. Any police officer attempting to search digital data possessed by a photographer should have a search warrant1 (Krages, 2011, p. 212). According to Lewis (2010, p.2), during the year 2009 unlawful conviction of a photographer named Robert Palmer cost the New York Police Department a total of $30 000. The amount of money was paid to the victim as damages because he was convicted unlawfully. Moreover, During December 19th, 2009, an amateur photographer was arrested in Lancashire Town for taking photos that were considered to be suspicious and triggering antisocial behavior by the police officers2 (Lewis, 2010, p. 5). The law enforcement officers questioned him under the anti-terrorism legislation and later arrested him. Nevertheless, during the year 2011, police officers arrested a photographer named Clint Fillinger for taking photos of a House Fire Crime Scene3 (Potter, 2012, p.1). In response to the unlawful arrests of photographers, Mickey Osterreicher, a general counsel of the National Press Photographers Association, says, â€Å"†¦police treat anyone with a camera as a suspect† (Potter, 2012, p.3). Moreover, John Timoney, the former police chief in Philadelphia and Miami confessed that there have been increased tension between police officers and photographers that has led to the unlawful arrests and convictions (Potter, 2012, p.4). Police officers have continued to violate the rights of

Essay on Psychopathology and Abnormal Psychology Essay Example for Free

Essay on Psychopathology and Abnormal Psychology Essay One of the most controversial aspects of society throughout history can be seen in the way society views people with illnesses. Often times, people persecute their fellowmen just because they do not seem â€Å"normal† or they seem to â€Å"not belong† with the current society. These problems have led to the development of a branch of psychology which aimed to look at the causes and other related information that formed these mental illnesses. This branch of psychology came to be known as abnormal psychology. Abnormal psychology is that segment of the field which studies mental illnesses and abnormal behavior. The field covers problems such as depression, obsession, and even sexual deviation. The field also traced the symptoms, etiology, effects, and how these illnesses are maintained. Before we study abnormal psychology though, we must first look into what people see as abnormal. Historically, many of the earliest civilizations attribute mental disorders and illnesses as manifestations of evil spirits; some even have practices which remove parts of the skull using primitive tools as a means of releasing these evil spirits. As time progressed though, people such as priests, shamans, and witch doctors have been employed to supposedly rid these individuals of the â€Å"malicious† spirits which inhabit their bodies. During the times of the Greeks and the Romans, diagnosing and identifying mental illnesses have become more scientific. However, during this period, mystical and supernatural explanations still prevail over the ideas of modern science. One example is Homer, according to him, mental illnesses are caused by God, taking away the minds of the victims. It is not until Hippocrates wrote numerous accounts, journals, essays, papers and other scholarly work that made the study more scientific. In his papers, Hippocrates wrote about things such as psychosis, mania, phobias, and paranoia. His theory, however, still is flawed because he attributed the illnesses to four fluids in the human body: black and yellow bile, phlegm, and blood. During the middle ages, more horrifying and disturbing accounts were given, According to studies, during this period, people with mental illnesses were classified as witches, and they were â€Å"hunted† so as to rid them of the physical world. It was further justified by the writing of the Malleus Malifacarum (Withc’s Hammer) in 1486. In 1563, a person by the name of Jahann Weyer wrote a book called De Praestigiis Daemonum (The Deception of Demons). The book discredited the beliefs that demons were the culprits in mental illnesses and instead brought out the point that natural causes may indeed result in abnormal behavior. He also looked at the possibility of the use of drugs as sparks which caused these said disorders. With his work, the study of mental abnormalities became more humanitarian and started to look for treatment, rather than damnation, for its victims. In 1769, Benjamin Rush, a professors of chemistry and medicine at the college of Philadelphia became the father of American psychiatry. He instituted reform by putting into action several changes such as better ventilation, separation and classification of violent and non-violent patients, and created programs for recreation catering to the patients who suffer from mental illness. By 1880, Dorthea Dix, a schoolteacher from Boston started a campaign which led to the opening of 32 psychiatric hospitals which prioritized the poor and the needy. Several other prominent people paved the way for the contemporary notion of psychopathology. Emil Kraeplin was the one who introduced to society different classifications of mental disorders. This led the way to a closer relationship between medicine and psychiatry. The classification focused on two important groups – the praecox or what is no known as the schizophrenics, and the manic-depressive psychopaths. He believed that these illnesses were caused by chemical imbalance and irregularities in other aspects of the person such as one’s metabolism. Another important person which helped develop the field of study was Clifford Beers. Beers himself suffered a mental breakdown but was able to overcome it. Upon his recovery, he wrote a book which he titled A Mind That Found Itself. Beers and his book were responsible for the foundation of the National Committee for Mental Hygiene, a branch of government which worked to prevent illnesses as well as make sure that any treatment conducted is classified as humane. Today, abnormal psychology focuses on the 4 D’s, these are distress, dysfunction, deviance, and danger. One should note though, that these 4 d’s are seen as judgments, not objective behavior. First of all is dysfunction. Dysfunction is defined as a difficult or abnormal function. In psychology, one of the most popular diseases caused by a dysfunction of the brain is schizophrenia. This disorder is caused by enlarged ventricles, reduced blood flow to the frontal lobe, and an excess of dopamine. Schizophrenia is a chronic disorder that is characterized by people who talk to themselves, yell at someone else which seem imaginary, and other symptoms. Another aspect of the psychopathology is distress. Distress in psychology can lead to numerous diseases, most popular of which are anorexia and bulimia. Often times, people who develop these conditions see it as a way of coping with negative emotions or painful feelings. Traumatic events in a person’s life may also trigger disorders in eating. Danger results in one of the most overlooked psychological disorder in an individual. Often times, notions of fear will develop into anxiety. Anxiety, unlike normal fear, can be characterized by four inherent characteristics. First of all, it is defined by a specific target; secondly, anxiety is experienced in response to the target of fear; third, the target feared by the individual is avoided; and finally anxiety tends to be more chronic. One of the most interesting in the 4 d’s is deviance. We might see something as deviant behavior, but we do not know is that this deviant behavior for us is the deviant’s â€Å"normal† function. This is why this is the most blurred classification out of all of the things that we characterize as abnormal. From here, there are three important viewpoints which look at mental disorders and their causes. These three models are the biological, psychosocial, and the socio-cultural models. First of all, the biological model looks at the brain as the cause of the abnormal behavior. According to proponents of this model, mental disorders are caused by the different chemical imbalances in the brain, and as such, leads to the difference in a person’s behavior. The socio-cultural approach looks at the role that society plays with regards to human behavior. According to its proponents, society and culture play a major role in determining if an individual will be labeled as â€Å"mentally ill† or has a mental disorder. Often times, this is where social deviance is seen; this is due to the idea that one is deviant for a culture may be the norms of the other. Finally, the psychosocial approach looks at underlying influences which are often times unconscious. This approach looks at the childhood and past experiences of the victim. Proponents of this approach are Sigmund Freud and Josef Brener. The approach theorizes that the disorder occurs when the individual becomes â€Å"fixated† to the stage wherein the negative experience has occurred. Looking at these evolutions in the field of abnormal psychology, it becomes positive enough that the approach, which was more of spiritual during earlier times, transforms itself into a more rational field of study. More importantly, these approaches lead us not to discriminate people with these disorders, but rather try to understand them and help them get better. Bibliography Abnormal Psychology. Blackwell Publishing. Retrieved April 10, 2009 from http://www. blackwellpublishing. com/intropsych/pdf/chapter15. pdf What is Abnormal Psychology? About. com. Retrieved April 10, 2009 from http://psychology. about. com/od/glossaryfromatoz/g/abnormalpsyc. htm Harris, Kevin. History of Abnormal Psychology. History of Psychology. Retrieved April 10, 2009 from http://www3. niu. edu/acad/psych/Millis/History/mainsheet. htm Bickard, Mark. The Nature of Psychopathology. Retrieved April 10, 2009 from http://www. lehigh. edu/~mhb0/psychopath. html

Decomposition of Hydrogen Peroxide Experiment

Decomposition of Hydrogen Peroxide Experiment A catalyst is a substance that makes a chemical reaction speed up or get faster. This can be things like the temperature, concentration, sold or even liquid, (bbc,2017). A catalyst essentially effects a chemical reaction, (bbc2017). For a chemical reaction to start the bonds must be broken for the reactants to fuse or react, (bbc,2017). To break the said bonds one needs energy, (gcse,2017). The name of the energy that breaks the bonds is called activation energy. When a chemical reaction happens the bonds of the reactants break (due to activation energy). After this the energy, must flow through a path for the reactants to react, (gcse,2017). Now because of the activation tacking up energy there can only be at one speed, (gcse,2017). When we add a cat list to this it creates an alternate pathway or a short cut for the energy to pass by. This is because the normal pat way is less effectiveGCSE,2017).ÂÂ   The diagram below shows a reactant going through a normal path way and on th at is going through on of a catalyst.ÂÂ   As you can see the rout of the normal path way is very tedious and long. Whereas the rout of the catalyst is much shorter. Types of catalyst A catalyst can be spilt into two main types. The first is the homogeneous. A homogenous catalyst is one that stays the same phase. The meaning can be found in the first part of word, this is Homo which means one or the same. Pretty much a homogeneous catalyst stays in the same phase, (chemguide,2017). Heterogeneous reactions are reaction with different phases. As Hetero means, different, (chemguide,2017). What is a phase? To explain this, we must first look at a mixture. Lets say that there was a stone in water. The stone was a solid and the water was a liquid. This represented a heterogeneous reaction. Now the same thing happened but there was no stone would be a homogeneous. The diagram below shows the different types of catalysts. (chemguide,2017) for the text and the diagram below. The catalyst it is shone that oxides work the best as catalyst. Aim: The aim or this experiment was to see what chemical was to see which catalyst would work the best in speeding up the decomposition of hydrogen peroxide. Hypothesis: Research suggest that iron nitrate will cause a violent exothermic reaction. With the materials, the group had this catalyst would have worked the best. Materials: 4 beakers 4 watch glances 2 stopwatches 1 spatula 1 scale Hydrogen peroxide Iron nitrate Manganese chloride Basic sault Measuring cylinder Method: The first item that were acquired were the personal protection equipment or ppe. The ese items consisted of safety glasses, rubber aprons and the disposable gloves. After this we collected out materials and went to the steel takes outside. A there were no power points we had to set the scales up inside at a free plug point. After the cake was set up we tested the decomposition of hydrogen peroxide without a catalyst. To do this we poured 25 ml of hydrogen peroxide in a beaker. After this 3the group timed the reaction with a stop watch. After the reaction was finished the results were recorded. This same experiment was done 4 time and all yielded the same result of two minutes. After this iron oxide was added to the hydrogen peroxide. This experiment was timed and done 3 times. The same was done with the other catalysts. All the catalysts were pounders. We measured them to .5-gram ad them added them into to the hydrogen peroxide. Possible risk solution Risk level Glass breakages Handle glass safely and walk with caution. medium Chemical Spills Be aware or your surroundings and handle with care. high Ingestion of chemicals Be sure not to ingest chemicals in this experiment. high Burn from and exothermic reaction Stand at a safe distance from the reaction always be alert high Chemicals come into contact with eyes Always keep safety glacises on as these devices a made to prevent chemicals going into the eyes high Catalyst First experiment Second experiment Final experiment iron nitrate 7.11 seconds 8.22 seconds 7.87 Basic sault 22.79 seconds 22.76 seconds 22.77 seconds Potassium Nitrate 19.22 seconds 14.12 seconds 17.89 seconds Manganese Chlorine 31.53 seconds 33.15 seconds 32.58 seconds Full results Experiment averages and observations Catalyst Average seconds Observation during the reactions Iron nitrate 7.69 Rapid exothermic reaction resulting in colour change and bubbling of the liquid. Basic sault 22.77 The mineral dispersed and did not make a noticeable change Potassium nitrate 17.07 Not a noticeable change but the crystals dispersed rapidly. Manganese Chloride 32.42 Made a chance but a very small one, this test was only a small bit faster than the normal reaction Discussion The experiment, The decomposition of Hydrogen Peroxide, provide very interesting results. The task was to aid the reaction by the addition of a catalyst. The experiment used a variation of salts, nitrates and chlorides. These catalysts were all 5 grams and were added to a 25 ml of hydrogen peroxide. The ration for this was 1:5. The first experiment that the group did was just recording the hydrogen peroxide by itself as this was used to get a base result. The group did this experiment four time with the decomposition taking 2 minutes to finish. This was the graphed into a line graph and the relax showed the consistent rate of reaction.ÂÂ   The main trend was that the nitrates did better than the other catalysts. The next catalyst added was the Iron nitrate(Fe(no3)). This catalyst produced the most interesting reaction as it created an exothermic reaction. The very moment the catalyst was added with the hydrogen peroxide it created profuse bubbling and the next second the it erupted into what looked like a boiling. the moment the hydrogen peroxide started bubbling the colour of the concoction changed from clear to a burnt orange. After the boiling, had stopped the concoction seemed to turn into a tinted yellow structure. This liquid was steaming and was clearly hot. This whole reaction was conducted three time and took 7.69 seconds on average. With this reaction, my hypothesis was proven to be supported. The second catalyst was Sodium chloride(NaCl) or basic salt this was by far the most uneventful reaction by far. The sodium chloride was added into the hydrogen peroxide and produced a few bubbles. This happen after the sodium chloride had dispersed. This reaction lasted for 22.77 seconds on average the reaction produced no colour or visible temperature change. The catalyst Potassium nitrate was also a very un-event full reaction. This did cause very rapid bubbling but it did not result in any noticeable change other than that. This catalyst like many others had no noticeable change. This was also tested times and had an average of 17.07. This was one of the shorter reactions. This aspect lead the group to believe that it was the second-best catalyst. This was also a reaction that stopped after it dissolved. The last and final catalyst was the Magnesium chloride was also an uneventful reaction. This was the longest reaction and therefore the worst catalyst of all the others. This catalyst sizzled for a long period bit it resulted in nothing happening. Evaluation The experiment was interesting as it was it had a range of mixed results. This was shown in this catalyst reaction as some experiments did barely anything and others had very violent notable reactions. There were four catalyst Iron nitrate, NaCl, Potassium nitrate, Magnesium Chloride. These Catalyst had varied effect on the decomposing reaction. For example, results showed that the nitrates did the best. But there was some problem met in this experiment. Due to the reactive nature of the Manganeses oxide. The group gelled together well and if was a good working relationship within the group. I feel as though the experiment could have been improved. As there may have been some key errors that could have occurred in the experiment. The experiment relayed on measurement for the entirety of it. The hydrogen peroxide had to be measured the catalysts had to be weighed and the time had to be counted by the stopwatch. These could have multiples of faults. Some main faults are in human error. Weather it man have been the wrong set up or parallax error these could all have been done. Another element that could have led to the experiments being wrong could have been inaccurate measuring tools. In some of the instrument the measuring lines could have been rubbed out or flawed. A way of fixing this would be if we used a more accurate item and used an IV Drip so that the use of the there would be a constant drip of fluid. After this I believe that it should be measured by a laser to bake sure that the amount of hydrogen peroxide is precise. The scales should have been swapped out with more accurate scales that pick up even the smallest changes of the object being weighed. When the experiment was, timed human error could have played the part of the timing as the person timing could have been just before or just after the catalyst was added. So, I propose that one would have a timer that was set to go off when the catalyst was added and would stop after the reaction would shop . This would get the most accurate reaction. I feel that is these modifications were done the experiment would have been much more accurate. In conclusion, the experiment of the decomposition of the Hydrogen peroxide reaction yielded interesting results. The hypothesis was supported as the nitrates did react better than the other catalysts.

Fashion and Women?s Movements in the Past Century Essay -- essays rese

  Ã‚  Ã‚  Ã‚  Ã‚  Today’s American women are following centuries old traditions of rebelling against society’s outlook on women around. Earlier in America’s history, it was unheard of for a woman to be in both the public and domestic sphere. Women were forced to spend most of their life in the domestic sphere, and wear ridiculous clothes everyday. For a long time, women have been degraded and pushed around, causing women to initial movements to change the way society treats women. In America, â€Å"the land of the free†, women have to fight for their equal rights. Reformers, such as Fanny Wright, Susan B. Anthony, Elizabeth Cady Stanton, Amelia Bloomer and many more have done so through their actions, and speeches. Nevertheless, in recent times fashion has become an available source of expression. It is a powerful tool to be able to be seen and not heard--but still get the message across. Since its humble beginnings, fashion has oftentimes just existed, but in the past century, it has existed as a form of expression, art, and liberation Now, women are still being influenced and challenged by the media and their peer, but slowly, more and more women are standing up for themselves.   Ã‚  Ã‚  Ã‚  Ã‚  Before the early to mid 1800’s, women were forced to squeeze into corsets made of whalebone, steel or buckram. It gave them the figure eight profile which resulted on a number of health problems, including their organs and body to become deformed. Over the corsets, women wore heavy layers of petticoats despite the weather. (Small Business Administration 3) Dresses emphasized the bust and hips, attempting to make women look very voluptuous. With the spread of commercialism, hundreds of new beauty products were introduced. These ever-popular restricting fashions were later outdated.   Ã‚  Ã‚  Ã‚  Ã‚  This fashion was not comfortable in any sort of the imagination, and a social reformer, Wright started to make a difference. She originated a modified version of dresses in the Victorian Age. This new dress was described as â€Å"long-sleeved, high-necked, and loose-fitting tunic over a pair of baggy trousers† (Banner 23). Anthony, Stanton, Bloomer, and along others started to wear this new comfortable fashion. Bloomer promoted this new fashion which become known as â€Å"Bloomers† in The Lily; a newspaper for women promoting â€Å"women’s suffrage, temp... ...shion of the nineties, which did provide liberation. By the end of the century, homosexuality was accepted and commonplace.   Ã‚  Ã‚  Ã‚  Ã‚  The future of women’s fashion is uncertain—in that shock value is harder to come by with each passing year. There is a concept in fashion that nothing is new, everything has been done before. This theory is coming closer to obvious reality, as fashion shows of recent years have visual throwbacks as late as the Victorian era. Although the direction is not yet decided, it is almost definite that women will use fashion as an important tool for expression and freedom in the future. Works Cited Banner, Lois W. Women in Modern America a Brief History. New York: Harcourt Brace Jovanovich, 1974. Guerrilla Girls. â€Å"Frequently Asked Questions.† Guerrilla Girls. 2005. 2 May 2005 . Small Business Administration. â€Å" Women’s History Month Amelia Jenks Bloomer.† Online Women’s Business Center. 16 Apr. 2002. 3 May 2005 . Thomas, Pauline Weston. â€Å"1950’s Glamour Fashion History 1950’s.† Fashion Era. 2005. 2 May 2005 . World Book, Inc. â€Å"The Rise of the Modern Women’s Movement.† The Modern Women’s Movement. 2004 ed. 1. 2 May 2005 .

Proclamation of student concerns :: essays research papers

Proclamation To Address Student Concerns About The Medium News Letter: Preamble: Presented on this day, November the nineteenth, in the year two thousand and three, as members of the Rutgers University community who are concerned and dissatisfied with the subject material that has been printed in the magazine The Medium, a student funded organization, we collectively agree that the following measures need to be met and addressed with as much cooperation as possible to facilitate in the propagation of unity amongst Rutgers University students, faculty, and staff. Rutgers University’s mission statement, as defined through the following excerpt, is required to be applied to every Rutgers University organization. All Rutgers University organizations are asked to abide by the mission statement of the university in order to foster a community that is cohesive and indivisible: â€Å"Rutgers, The State University of New Jersey is committed to the ideals of excellence in fostering an enriching learning community of students, faculty and staff from a broad spectrum of nations, cultures, and historical perspectives. Diversity is an integral component of human experience, and encompasses but is not limited to issues of race, ethnicity, culture, social class, national origin, gender, age, religious beliefs, sexual orientation mental ability, and physical ability. Our collective goal is to create an institutional consciousness of diversity reinforced with equity and excellence through our policies, practices, and programs of inclusion, non-discrimination, and pluralism for all members of the University Community.† WHERE AS:  Ã‚  Ã‚  Ã‚  Ã‚  The mission of the university is stated above, The Medium must question its current relevance to the university’s mission. While membership is not neglected on the basis of â€Å"†¦race, sex, handicap, age, sexual orientation, or political and religious affiliation (Medium Constitution)†, the publication itself does not agree with the university’s mission, nor does it provide an outlet for diversity and respect of other cultures, races, and sexual orientations. WHERE AS:   Ã‚  Ã‚  Ã‚  Ã‚  The Medium has published and continues to publish ‘hate speech’, the environment in which said magazine has and is creating one of racial hostility. Community lines are drawn due to racial, religious, gender, and sexual orientation differences, causing the Rutgers University community to be disjointed and without proper unanimity and accord. WHERE AS:   Ã‚  Ã‚  Ã‚  Ã‚  The Medium has fostered an atmosphere of antagonism, the safety of students, regardless of color, creed, gender, and sexual orientation are in danger. Although opinions are without credit to those they might endanger, the physical sight of such opinions places the Rutgers community in a state of alert and fear.

Compare the two nineteenth century horror stories Essay

Compare the two nineteenth century horror stories, ‘The Black Cat’ and ‘The Tell-Tale Heart’ by Edgar Allan Poe, showing how Poe uses a range of techniques to make his stories dramatic and effective. ‘The Black Cat’ and ‘The Tell-Tale Heart’ are two of the earliest horror stories ever written; they were written in the 1840’s by the American author Edgar Allan Poe. Poe was born in Boston Massachusetts in 1809. He tragically died in 1849 following a life of alcohol and drugs. ‘The Black Cat’ tells us about a man who is in a condemned cell. He is on death row and reflecting on his life and the reason behind the situation he is in. He tells the reader about his love for animals and how he married early in life. His wife allowed him to buy a black cat who never left his master’s side. However, the narrator tells how he became an alcoholic and started to mistreat his wife and pets. On returning home one night he seized the cat and in fright the cat had bitten him. This made him angry and therefore he cut out one of the cat’s eyes. A few days later he took the cat, slipped a noose around its neck and hung it from a limb of a tree. That night the house burnt down and engraved on the wall was the figure of a cat. Later on in the story the narrator tells us of how he found a cat that closely resembled the one he had killed. The cat would never leave his side which started to make him hate the creature. He was walking down the steps of the cellar one day with his wife when the cat followed and sent him headlong down the steps. In fury he picked up an axe and aimed a blow at the cat. His wife tried to stop him so he buried the axe into her brain. He buried the body in the wall of the cellar. The police found the body as the man become cocky and tapped on the wall where he had buried his wife, there was a wailing sound and the police uncovered the body with the cat on the corpses head. ‘The Tell-Tale Heart’ tells us about a man who has been accused of being mad. He looked after an old man who had a ‘vulture eye’. His eye was a pale blue and had a film over it. Whenever the eye fell upon the narrator, it made his blood run cold. Therefore he decided to kill the old man. In the week before he killed him the narrator tells us about how he crept into the old man’s bedroom every night at midnight, trying to find the right moment to kill him. On the eighth night the old man became aware that someone was in his room. The narrator says how he could hear the man’s heart beating in his chest and was frightened that the neighbours would hear it. He ran into the room; seized the man out of his bed and pulled the bed on top of him. He then took the planks from the flooring of the bedroom and placed the body there. Once he had replaced the floorboards the police arrived saying that a neighbour had heard a shriek and they wished to search the property. He led them towards the old man’s bedroom and placed some chairs out for them on the exact spot of the body. He began to make typical chat with the officers but could hear the heart of the old man beating louder and louder until it drew the narrator mad and he confessed to the murder. Both stories have typical features of a modern horror story – blood, murder, the murders conscience and supernatural aspects. However, the structure of the stories differ. ‘The Black Cat’ is a longer story and is more detailed. It includes more background description. â€Å"I was especially fond of animals, and was indulged by my parents with a great variety of pets.† This quote shows that ‘The Black Cat’ tells us about the background of the narrator since he was a young boy. ‘The Tell-Tale Heart’ is more concise and includes some very detailed sections but less background. â€Å"Presently, I heart a slight groan, and I knew it was the groan of mortal terror. It was not a groan of pain or of grief — Oh no! It was a low stifled sound that arises from the bottom of the soul when overcharged with awe.† This quote shows that ‘The Tell-Tale Heart’ has some very detailed sections as the narrator goes into depth about the noise that the old man made. The two narrators have various things in common; they both tell the story in first person and use eyes as an important feature in the story. In the opening paragraph both narrators also say that they have been accused of madness but deny the accusation. â€Å"Mad indeed would I be to expect it, In a case where my very senses reject their own evidence. Yet, mad am I not.† This quote from ‘The Black Cat’ supports my point that the narrator has been accused of being mad but denies it. â€Å"But why WILL you say that I am mad?† This quote from ‘The Tell-Tale Heart’ also supports my point as it is from the opening paragraph of the story and the narrator is asking why he is being accused of being mad. The significant differences between the two narrators are; ‘The Black Cat’ gives a more in-depth background about his life before the present day whereas ‘The Tell-Tale Heart’ goes straight into the present. ‘The Black Cat’ is also set in different rooms of the house and other areas where as ‘The Tell-Tale Heart’ is set in just one room. The relationship between the readier is also different. ‘The Black Cat’ is wrote as if the narrator is writing a letter whereas ‘The Tell-Tale Heart’ is wrote as if the narrator is actually speaking to the reader. â€Å"For the most wild, yet most homely narrative which I am about to pen.† These words suggest to me that ‘The Black Cat’ tells the story as if he is writing a letter. â€Å"How then am I mad?† This rhetorical question shows that the narrator tells the story as if he is actually talking to the reader. The two narrators in the story get caught as they become too over confident about the hiding place of their victims. They both lead the police to the place that the bodies are buried. Sound is also a major part in the reason for the two narrators getting caught. Poe uses a range of visual and sound techniques to make the stories dramatic and effectible. In both stories sound plays a major part in the narrator’s getting caught. â€Å"Then quickly swelling into one long, loud and continuous scream, utterly anomalous and inhuman.† This quote from ‘The Black Cat’ suggests to me that the points I have made are correct. The sound makes the story more dramatic and suspicious. It also leads the police to the corpse. â€Å"But the beating of the heart grew louder, LOUDER! I thought the heart must burst.† This quote also suggests to me that the beating of the heart made the murderer go mad and confess. It also adds an eerie effect to the story. Poe also uses visual description in the stories. â€Å"The corpse, already greatly decayed and clotted with gore, stood erect before the eyes of the spectators. Upon its head, with red extended mouth and solitary eyes of fire†¦Ã¢â‚¬  This phrase of writing from ‘The Black Cat’ goes into great visual detail about the corpse which makes it a lot easier to picture the story in your head. The amount of description sets the scene very effectively and makes the reader feel like there telling the story from their own personal experience. The use of evil words such as ‘greatly decayed’ and ‘clotted with gore’ also emphasise the fear and terror of the story. Poe uses a range of imagery in the stories; including alliteration, similes, metaphors, onomatopoeias, and rhetorical questions. These all make the stories dramatic and keep the reader interested. In ‘The Tell-Tale Heart’ Edgar Allan Poe uses a lot of onomatopoeia and metaphors. â€Å"my blood ran cold† This quote proves the point that Poe uses metaphors in this story. â€Å"Like the thread of a spider† This also proves that Poe uses Similes in this story. Both of these enhance the story as they make it more dramatic and effective. In ‘The Black Cat’ Edgar Allan Poe uses a lot of alliteration, metaphors and personification. â€Å"My tenderness of heart† This quote is particularly important as later on in the story the narrators heart is the complete opposite from tender. â€Å"Grew with my growth† This quote from the story shows alliteration. By using both of these quotes the writer is making the story more effective as he is making it more interesting to read. He is also encourage interpretation from the reader and helping them to feel the emotion of the characters. Poe also uses language devices to make the stories dramatic and effective. These include rhythm, repetition, and rhetorical questions. In ‘The Tell-Tale Heart’. Edgar Allan Poe uses a large amount of rhetorical questions. â€Å"How then am I mad?† This is effective in the story as it involves the reader. It does so by encouraging the reader to reflect upon the question and therefore get involved more with the story. Poe also uses repetition. â€Å"He had found all in vain. All in vain; because Death, in approaching him†¦.† The repetitive phrase all in vain, tells us of the narrators joy at the old mans terror. He also uses a capital ‘D’ in death. This infers he is using death as a name, suggesting that the old man is death. In ‘The Black Cat’ Poe uses plenty of rhythm and repetition. â€Å"Have terrified — Have tortured — Have destroyed me.† In this quote Edgar Allan Poe has repeated the word ‘have’. He has used a rhythm by pausing at the end of each word and the dashes indicate an intensity of emotions. He has also used evil words such a ‘terrified’ and ‘tortured’ which again emphasise the fear and terror of the story. This makes the story more dramatic. In both stories Poe also uses capital letters to emphasise words this gives an immediate dramatic impact. In conclusion, Poe uses a range of techniques to make his stories dramatic and effective, many of these are still used by horror writers today. Although ‘The Black Cat’ and ‘The Tell-Tale Heart’ are similar in numerous ways, Poe uses different techniques in each one to make the stories effective in their own particular way.

Experiment on Photocromism and Piezochromism

Introduction This experiment investigates an oxidative coupling reaction in an to synthesis thermodynamically dimmer from 2,4,5-trippingly-1 H-immediate. The resulting compound was investigated for both photometric and piezoelectric properties by way of formation of a stable radical, utilizing visual observations and UP-Visas as a means of distinction. Both the oxidative coupling reaction and the dimmers interaction with light re depicted In the reactions in figure 1.Figure 1 : Oxidative Coupling reaction of 2,4,5-trippingly-1 H-imitated Experimental Ethanol (mall), potassium hydroxide (8. Egg, 2. Moll) and water (ml) were added in order to H-imitated (0. Egg, 3. Moll). The mixture was stirred until clear before It was cooled to 5 co. A solution of potassium Africanized (3. 0021 g, 9. Moll), water (mall) and ethanol (mall) was prepared and added drowses Into the mixture ensuring the temperature did not rise above 10 co.A grey precipitate was Isolated from the yellow mixture through v acuum filtration and washed with water (ml x 5) and 50% aqueous ethanol. The mixture was dried under vacuum suction and the melting point was determined. Yield: 0. Egg, 90. 8% m. P-199. 8-200. ICC. A portion of the dimmer (0. 0305 g, 0. Molotov) was quantitatively dissolved in ml of toluene. The solution was left for min until colorless. The UP- Visas spectra was recorded for the colorless sample.

Analyzing a Major Issue, Domestic Violence as an Whole Essay

Although there are now laws against domestic violence, the issue still seems to be present in the 21st century. Once given an blind eye to is existence for decades people are now forced to face the fact that domestic violence is an major issue no matter when and where it may occur. In this essay I will be addressing the issues of: What is has been done to try and stop this violence and help the victims involved? What psychological issues that may fuel the particular act of violence? What challenges that law enforcement agencies and victims face pertaining to domestic violence and how might these challenges be addressed. And whether are not if I agree with the external peer reviewed references arguments based on domestic violence? Throughout the years domestic violence in our country was never a topic that was spoken about outside of our homes. It wasn’t until 1984 that Congress decided to bring this issue out of the darkness by inventing the Family Violence Prevention and Service Act (P. L 98-457) ( https://www. hildwelfare. gov/pubs/usermanuals/domesticviolence/domesticviolencec. cfm). This act was proposed to assist States with their efforts to increase public awareness about domestic violence and to find ways to provide government funding to provide shelter and victim assistance. I for one think that congress did the right thing for this time period in our history. But it wasn’t until ten years later that the Violence against Women Act (VAWA) (h ttps://www. childwelfare. gov/pubs/usermanuals/domesticviolence/domesticviolencec. cfm) came into play. This law helped the government establish the four titles that are within the VAWA act: Safe Homes for Women, Civil Rights for Women and equal Justice for Women in the Courts, Protections for Battered Immigrant Women and Children, and the Safe Street Act. A few years after that a new act was set into place called Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWOR). This act addresses the restraint put on battered individuals looking for work and support due to their domestic violence circumstances. This amendment give each state a loop hole to â€Å"temporarily exempt identified victims of domestic violence from meeting certain time limits and other work requirements. † (https://www. childwelfare. gov/pubs/usermanuals/domesticviolence/domesticviolencec. cfm) These acts as also helped to lead the way for â€Å"Congress to pass a law making it a federal crime for people convicted of domestic violence to own a gun (18 U. S. C. 922(g)(9)), hoping to reduce the injuries that repeat domestic violence offenders might inflict. The U. S.  Supreme Court upheld the law in the case of United States v. Hayes (2009), ruling that the law applied to any conviction based on an act of domestic violence, even if a defendant was not convicted explicitly of the crime of domestic violence. †( http://www. nolo. com/legal-encyclopedia/domestic-violence-33813. html). Domestic violence according to our Psychology 110 textbook (Franzoi, 2009) could be linked to self-regulation failure (P. 66), ambivalent sexism behavior (P. 213), and aggression associated cues (P. 441) experienced in the home. Self-regulation failure seems to become present in any situation where one spouse or the other is putting aside his/her wants to do what is considered important to the relationship, this kind of sacrifice sometimes only back fires later. Any minor incident or disagreement could cause an individual to snap that has been given up their leisure time to do something else that was thought to be important. Let’s consider the psychological concept called ambivalent sexism behavior that is found on page 213 of Franzoi, 2009. This behavior is described as â€Å"behavior directed against women based on both positive and negative attitudes including hostility and benevolence, rather than uniform dislike. The example given stated that Turkey and Brazil men and women who endorse hostile and benevolent sexist beliefs towards women justify violence against wives when they challenge their husbands’ authority or violate traditional gender roles. †(Franzoi,2009). But this is not the case in aggression-associated cues located on page 441. These particular cues seem to trigger domestic violence in the households. Some of the well-known aggression cues are weapons such as: baseball bats, sticks, knives, and guns. The less recognized cues would be hostile physical characteristics, and negative attitudes coming from either party involved in a dispute. When domestic violence is present in a home it often goes unreported. In these situations it becomes hard for police officials to step in and protect the victim. â€Å"Police and prosecutors face two common problems when it comes to arresting, charging, and prosecuting domestic violence. First, victims of domestic violence are often reluctant to report the abuse. Abuse victims may hope that the abuse was an isolated act that will not be repeated. Are secondly they may be fearful that reporting the violence will only goad their attacker into further violence. If a woman and her children are dependent on their abuser’s income, the mother may fear that reporting the violence will result in loss of financial support. Understandable though such reactions may be, the result is that most crimes of domestic violence go unreported. The last thing that makes these kinds of cases hard to prosecute is that even when victims of domestic violence report attacks to the police, victims often refuse to testify against their attackers at trial. As defendants have a constitutional right to confront and cross-examine their accusers, prosecutors usually cannot offer domestic violence victims’ statements to the police into evidence in lieu of the victims’ actual testimony in court. As a result, prosecutors must sometimes dismiss domestic violence charges. The combination of failing to report and refusing to cooperate with prosecutors makes domestic violence one of the hardest crimes to successfully prosecute. (http://www. nolo. com/legal-encyclopedia/domestic-violence-33813. html). † Victimized individuals of domestic disputes could help themselves and others by reporting the crime to the proper authorities no matter how big are small the dispute. But I can’t argue against the statement of: â€Å"domestic violence has been a constant despite differences in cultures or political regimes.. Whether it takes the form of sexual assault, physical assault, homicide, or one of the other myriad forms of abuse, societies struggling with defining otherwise criminal and abhorrent behavior rooted within a domestic, oftentimes familial, relationship. Attitudes of shame, silence, guilt, and fear battle against centuries of entitlement, tradition, and even theological tenets. (Shelley M. Santry, 2012). Often making it harder for the victim to report the crime sense he/she in so many words are â€Å"hoping that the abuse was an isolated incident† that won’t happen again. I do agree with the statement of â€Å"reporting the crime lets the abuser know that his/her behavior will not be tolerated by you or law enforcement. † (Sherman & Berk, 1984). I would also recommend that the victim of domestic violence should look for support programs and organizations that offer the help to get out a bad situation. These sorts of support groups and organizations could be run by protection agency and law enforcement to secure the safety and wellbeing of the victims involved. Prosecutors and other agencies involved in the criminal justice program could provide a service similar to witness protection for the victims of domestic violence to ensure that he/she goes to court to testify against their attacker. I agree with the statement made in (JENNETT, 2012) stating that â€Å"Changing policing practices reflect these attitudinal changes and police play a crucial role in ensuring that the rights of the battered are upheld. † Although this isn’t an easy process let’s consider the fact that everyone doesn’t see eye to eye on the issue of domestic violence. What if a police officer is an abuser him/herself? Then of course the officer that is called out isn’t going to do too much to protect the victim from the abuser. But I do disagree with the statement of â€Å"Police are not called on to protect victims of domestic violence until someone reports an incident. † (JENNETT, 2012). This is not always the case more than likely if an officer sees domestic violence in public he/she will intervene and try to settle the conflict. But these recommendations would be useless if you were a resident that resided inside the Topeka, Kansas. City limits. I honestly disagree with the decision of this city council â€Å"to decriminalize misdemeanor domestic violence cases. † (Shelley M. Santry, 2012). According to the information published this decision â€Å"came in response to the Shawnee County District Attorney, Chad Taylor, notifying the city that the District Attorney’s office would no longer prosecute such cases arising within Topeka city limits due to budgetary constraints. And my question to this article is â€Å"What about the Equal Protection Clause of the Fourteenth Amendment? †( http://www. loc. gov/rr/program/bib/ourdocs/14thamendment. html). And the answers to these questions are yes! Depending on where you live and the state in which you reside. In my conclusion the main issue at hand goes further than domestic violence, there are criminal and civil procedures that exist in all states and countries that may or may not view this issue as a priority compared to other crimes.

Lord of the Flies Literary Analysis

Lord of the Flies, a novel by William Golding, reflects upon the very core of human beings. Golding described human beings as innately evil. He also showed readers that all it takes to bring humans’ true nature out is by being in an unknown environment that is free of laws. Being surrounded by mysterious creatures in an unknown land, the stranded boys are left for dead. In the small world without adults, the boys slowly corrupt in to follow their instinct to satisfy their immediate desires.By being in a microcosm of society with no rules or restriction, the boys begin to seek absolute power. By setting the novel in an island without adults, Golding shows how civilization can quickly deteriorate into savagery. The theme of peace and democracy is thoroughly described in the story when the boys camped out near the beach. At the beginning of the book, it was evident that the boys had an instinct to live peacefully and by the rules in order to avoid chaos. Though some boys created trouble for others, they all obeyed the orders of the leader.The boys voted for a leader democratically in order to prevent a person from having too much power and by this process, we could see that the boys wanted to be fair in who gets to be the leader. To the boys, the beach symbolizes a second home that can keep them safe from the intimidating island. It was a place where they can catch sight of a ship without interruption and it gave them a higher chance of being rescued. The beach also represents safety and a place where rules protect the boys. All the boys have a sense of civilization in them at the beach and avoid making â€Å"wrong† actions.Even the troublemaker Jack said that they’ve â€Å"got to have rules and obey them. After all, we’re not savages. We’re English, and the English are best at everything. So we’ve got to do the right things. † (Page 59-60) This line from Jack shows that everyone wanted to be â€Å"civilized† and developed. They didn’t want to be â€Å"savages† since they had an instinct to act righteously and because they didn’t want to degrade themselves as to being savages. However, as the scenery changes, we can see that the boys are slowly becoming blind for power.A conflict of instincts can be seen when the boys confront in the mountain. Up until now, the boys were living peacefully near the beach. However, as time flowed pass, the boys began to crave to satisfy their other needs. Some began to neglect their duties and went off to play. This sign of neglecting shows the readers that the boys are starting to satisfy their own â€Å"desires†. Jack and the other hunters showed signs of corruption when they abandoned their â€Å"fire† duty. Although they were given such an important task, they weren’t able to work to Ralph’s expectations.After a ship has passed by the island, Ralph and Jack conflicted once more. During this confrontatio n, Jack accidentally destroyed half of Piggy’s glasses. The breaking of Piggy’s glasses symbolizes many things. First of all, it symbolizes that many of the boys are having a conflict between their instinct to live peacefully and their instinct to satisfy their immediate need. Secondly, it represented the turning point of the novel. And finally, the breaking of Piggy’s glasses symbolizes a break in the boys’ teamwork. After this event, a split between Ralph and Jack was evident.Near the last scenes of the novel, the readers can see that savagery took over civilization. When the hunters turned against Ralph and the little’uns and formed their own group in â€Å"Castle Rock†, it showed the readers just how much the hunters have corrupted. Unlike civilized people, the hunters began to paint their faces with blood and began to worship idols in order to celebrate their catch. Another significant change in the hunters is that the hunters wouldnâ⠂¬â„¢t hesitate to torture boys that were once friends and family.At the end of the novel, a huge boulder crushed Piggy. This symbolizes many things. First of all, it shows the readers the change in the hunters. At the beginning of the novel, Roger was a boy that wouldn’t throw a rock straight at a person. However, as the novel progresses, Roger became ruthless and was willing to hurl a boulder at Piggy. Furthermore, Piggy’s death symbolizes the death of an intellect. It shows us that savagery has taken over civilization and that rules will no longer influence the boys anymore.As the novel processes and the scenery changes, the readers can witness a significant change in the boys’ actions and thoughts. The boys’ actions in the beach and their actions in Castle Rock were significantly different. Unlike their â€Å"civilized† self, the unknown environment slowly turned these boys’ mental self and physical self. They became more interested in s atisfying their desires than to do the â€Å"right† thing. By placing the boys in an island with no adult influence, William Golding shows how the environment changes human beings into savages. Lord of the Flies Literary Analysis Lord of the Flies, a novel by William Golding, reflects upon the very core of human beings. Golding described human beings as innately evil. He also showed readers that all it takes to bring humans’ true nature out is by being in an unknown environment that is free of laws. Being surrounded by mysterious creatures in an unknown land, the stranded boys are left for dead. In the small world without adults, the boys slowly corrupt in to follow their instinct to satisfy their immediate desires.By being in a microcosm of society with no rules or restriction, the boys begin to seek absolute power. By setting the novel in an island without adults, Golding shows how civilization can quickly deteriorate into savagery. The theme of peace and democracy is thoroughly described in the story when the boys camped out near the beach. At the beginning of the book, it was evident that the boys had an instinct to live peacefully and by the rules in order to avoid chaos. Though some boys created trouble for others, they all obeyed the orders of the leader.The boys voted for a leader democratically in order to prevent a person from having too much power and by this process, we could see that the boys wanted to be fair in who gets to be the leader. To the boys, the beach symbolizes a second home that can keep them safe from the intimidating island. It was a place where they can catch sight of a ship without interruption and it gave them a higher chance of being rescued. The beach also represents safety and a place where rules protect the boys. All the boys have a sense of civilization in them at the beach and avoid making â€Å"wrong† actions.Even the troublemaker Jack said that they’ve â€Å"got to have rules and obey them. After all, we’re not savages. We’re English, and the English are best at everything. So we’ve got to do the right things. † (Page 59-60) This line from Jack shows that everyone wanted to be â€Å"civilized† and developed. They didn’t want to be â€Å"savages† since they had an instinct to act righteously and because they didn’t want to degrade themselves as to being savages. However, as the scenery changes, we can see that the boys are slowly becoming blind for power.A conflict of instincts can be seen when the boys confront in the mountain. Up until now, the boys were living peacefully near the beach. However, as time flowed pass, the boys began to crave to satisfy their other needs. Some began to neglect their duties and went off to play. This sign of neglecting shows the readers that the boys are starting to satisfy their own â€Å"desires†. Jack and the other hunters showed signs of corruption when they abandoned their â€Å"fire† duty. Although they were given such an important task, they weren’t able to work to Ralph’s expectations.After a ship has passed by the island, Ralph and Jack conflicted once more. During this confrontatio n, Jack accidentally destroyed half of Piggy’s glasses. The breaking of Piggy’s glasses symbolizes many things. First of all, it symbolizes that many of the boys are having a conflict between their instinct to live peacefully and their instinct to satisfy their immediate need. Secondly, it represented the turning point of the novel. And finally, the breaking of Piggy’s glasses symbolizes a break in the boys’ teamwork. After this event, a split between Ralph and Jack was evident.Near the last scenes of the novel, the readers can see that savagery took over civilization. When the hunters turned against Ralph and the little’uns and formed their own group in â€Å"Castle Rock†, it showed the readers just how much the hunters have corrupted. Unlike civilized people, the hunters began to paint their faces with blood and began to worship idols in order to celebrate their catch. Another significant change in the hunters is that the hunters wouldnâ⠂¬â„¢t hesitate to torture boys that were once friends and family.At the end of the novel, a huge boulder crushed Piggy. This symbolizes many things. First of all, it shows the readers the change in the hunters. At the beginning of the novel, Roger was a boy that wouldn’t throw a rock straight at a person. However, as the novel progresses, Roger became ruthless and was willing to hurl a boulder at Piggy. Furthermore, Piggy’s death symbolizes the death of an intellect. It shows us that savagery has taken over civilization and that rules will no longer influence the boys anymore.As the novel processes and the scenery changes, the readers can witness a significant change in the boys’ actions and thoughts. The boys’ actions in the beach and their actions in Castle Rock were significantly different. Unlike their â€Å"civilized† self, the unknown environment slowly turned these boys’ mental self and physical self. They became more interested in s atisfying their desires than to do the â€Å"right† thing. By placing the boys in an island with no adult influence, William Golding shows how the environment changes human beings into savages.

Patient And Tumor Characteristics Health And Social Care Essay

Between January 2004 and June 2010, 160 patients underwent computing machine imaging guided transdermal cryoablation for lung tumours at our establishment. Of these patients, histologically proved phase I lung malignant neoplastic disease patients with more than one twelvemonth of followup, were retrospectively reviewed. All of these patients were considered to be medically inoperable with Charlson comorbidity index of 3 or greater. Follow-up was based chiefly on computed imaging. There were 22 patients with 34 tumours who underwent 25 Sessionss of cryoablation intervention. Complications were pneumothoraces in 7 interventions ( 28 % , chest tubing required in one intervention ) , and pleural gushs in 8 interventions ( 31 % ) . The observation period ranged from 12-68 months, mean 29 ±19 months, average 23 months. Local tumour patterned advance was observed in one tumour ( 3 % ) . Mean local tumour progression-free interval was 69 ±2 months. One patient died of lung malignant neo plastic disease patterned advance at 68 months. Two patients died of acute aggravations of idiopathic pneumonic fibrosis which were non considered to be straight associated with cryoablation, at 12 and 18 months, severally. The overall 2- and 3-year endurances were 88 % and 88 % , severally. Mean overall endurance was 62 ±4 months. Median overall endurance was 68 months. The disease-free 2- and 3-year endurances were 78 % and 67 % , severally. Average disease-free endurance was 46 ±6 months. Pneumonic map trials were done in 16 patients ( 18 interventions ) before and after cryoablation. Percentage of predicted critical capacity, and per centum of predicted forced expiratory volume in 1 2nd, did non differ significantly before and after cryoablation ( 93 ±23 versus 90 ±21, and 70 ±11 versus 70 ±12, severally ) .Conclusions/SignificanceAlthough farther accretion of informations is necessary sing efficaciousness, cryoablation may be a executable option in medically inopera ble phase I lung malignant neoplastic disease patients. Travel to:IntroductionSurgical resection is presently the criterion intervention for phase I non-small cell lung malignant neoplastic disease ( NSCLC ) . However, in patients who are medically inoperable due to important comorbidities, other intervention modes need to be considered. The non-surgical direction of early phase lung malignant neoplastic disease is presently an spread outing field. These include stereotactic organic structure radiation therapy ( SBRT ) and thermic ablative processs such as radiofrequency extirpation ( RFA ) and micro-cook extirpation [ 1 ] , [ 2 ] , [ 3 ] , [ 4 ] , [ 5 ] , [ 6 ] . Transdermal cryoablation is besides presently germinating as a minimally invasive, and potentially effectual, local intervention for lung tumours [ 7 ] , [ 8 ] , [ 9 ] , [ 10 ] . This process, largely used when surgical resection is contraindicated, is presently under rating as a possible complementary therapy for patients with primary lung malignant neoplastic diseases every bi t good as metastatic lung tumours. We have, to day of the month, treated more than 300 lung tumours in more than 200 patients with acceptable feasibleness and efficaciousness. Of these patients, in the present survey, we retrospectively analyzed the midterm results of phase I NSCLC patients treated with cryoablation. Travel to:Materials and MethodsEthical motivesThis survey protocol was approved by Keio University institutional reappraisal board ( blessing ID: 14-23 ) . Written informed consent was obtained from each participant in conformity with the Declaration of Helsinki.Choice of patientsBetween January 2004 and August 2010, 160 patients underwent cryoablation for lung tumours at our establishment. Of these patients, we retrospectively reviewed our experience with cryoablation for the primary intervention of phase I NSCLC in medically inoperable patients, with more than one twelvemonth of followup. The tumours which presented as multiple tumours in one patient, were clinically considered as synchronal or metachronous primary lung malignant neoplastic diseases to be eligible for this survey. Some of these patients have been reported antecedently [ 7 ] , [ 9 ] . Prior to sing cryoablation, patients with histologically diagnosed NSCLC were routinely staged with chest-to-pelvis computed imaging ( CT ) , encephalon magnetic resonance imagination ( MRI ) or CT, and most of the patients besides underwent a antielectron emanation tomographic ( PET ) scan. Bone scintigraphy was done if PET scan was non performed. Patients with hilar or mediastinal lymph nodes greater than 1 centimeter in the shortest axis, a positive PET scan consequence, or both, underwent endobronchial echography guided needle biopsy, or mediastinoscopy. The inclusion standard for this survey were patients who were considered medically inoperable because of hazards such as impaired cardiac map, hapless pneumonic map, and/or other comorbidities, i.e. , Charlson comorbidity index ( CCI ) [ 11 ] & A ; gt ; = 3. The patients ‘ desires to avoid surgery in association with their medical comorbidities were besides accounted for. The exclusion standards were as follows: ( 1 ) Eastern Cooperative Oncology Group ( ECOG ) mark of 2 or more. ( 2 ) Platelet count of less than 50,000/ µL. ( 3 ) Prothrombin clip international normalized ratio of more than 1.5. ( 4 ) No suited manner for the interpolation of investigations due to interference by major vasculatures, air passages or mediastinal constructions. ( 5 ) Incapable of cooperation during the cryoablation process. All patients were evaluated by representatives from pulmonologists, interventional radiotherapists, and pectoral sawboness to find inoperability and suitableness for cryoabla tion.Cryoablation processThe process of transdermal cryoablation was performed under local anaesthesia as antecedently described [ 7 ] . Under a multidetector-row CT scanner with multi-slice CT fluoroscopy maps ( Aquilion 64 ; Toshiba Med. Co. Ltd. , Tokyo, Japan ) , utilizing an outer interpolation sheath, a 1.7-mm-diameter cryoprobe ( CRYOcare Cryosurgical Unit ; Endocare, Irvine, CA ) was inserted into the targeted nodule under fluoroscopic CT counsel. Multiple investigations were at the same time inserted if the extirpation border was considered to be deficient with merely one investigation. The cryoprobe uses high-pressure Ar and He gases for stop deading and dissolving, severally, based on the Joule-Thompson rule. Cryoablation consisted of three rhythms of freeze, 5, 10, and 10 proceedingss each. The tip of the cryoprobe reaches about ?130 & A ; deg ; C during stop deading. This was followed by dissolving until the temperature of the cryoprobe reached 20 & A ; deg ; C, and so a 3rd rhythm of freeze ( 10 proceedingss ) followed by dissolving. Fibrin gum was infused into the outer sheath at the clip of cryoprobe remotion to cut down the hazards of hemothoraces and pneumothoraces. Whole lung CT scans were taken at the terminals of each of the processs. Chest radiogram were besides taken two hours after, the following twenty-four hours, and the twenty-four hours after each of the processs to look into for complications such as hemothoraces or pneumothoraces. The patients were discharged on the 2nd postoperative twenty-four hours if there were no complications.Follow-up after cryoablationFollow-up chest-to-pelvis CT scans with contrast sweetening were carried out at 1-month and so at 3 to 6 months intervals after cryoablation. We confirmed local patterned advance when there was a uninterrupted focal or diffuse expansion of the ablated lesion on CT. Furthermore, even when no expansion was seen, we regarded it as local patterned advance if the size of partial s weetening in the tumour continuously increased. As for the sensing of distant metastases, encephalon MRI or CT was done every 3 to 6 months. Favored scan or bone scintigraphy was done if considered to be necessary.Pneumonic map trialPneumonic map trial was done in patients who could adequately execute the trial, before, and 3 to 6 months after cryoablation.Statistical methodsLocal tumour progression-free intervals, and overall and disease-free endurances, were calculated with the Kaplan-Meier method. Pneumonic map trials were compared with the mated t trial. The statistical package bundle SPSS 17.0 ( SPSS Inc, Chicago, Ill ) was used for all analyses. P values smaller than 0.05 was considered to be statistically important. Travel to:ConsequencesDuring the survey period, 22 patients with 34 tumours underwent 25 Sessionss of lung cryoablation interventions for clinical phase I NSCLC. These patients were retrospectively reviewed. None of the patients had mediastinal or hilar lymph nodes greater than 1 centimeter in the shortest axis, or a positive PET scan consequence of the mediastinal or hilar lymph nodes. Fifteen patients had individual tumours, which were all treated in one session. Three patients had 2 tumours. The 2 tumours were found synchronously in all 3 patients, and were treated as one session per patient. Four patients had 3 tumours. In 2 of these patients, the 3 tumours were found synchronously, and were treated as one session per patient. In both of the staying 2 patients, 2 tumours were synchronal and one was metachronous. The 2 synchronal tumours were treated in one session in each of the patients. The metachronous tumours were treated as another session in both patients. One patient had 4 tumours. Two of these tumours were found synchronously and were treated in one session. Other 2 metachronous tumours were found at the same clip, and were treated in one session. The patient and tumour features are described in Table 1. The average maximum tumour diameter was 1.4 ±0.6 centimeter ( range 0.5-3.0 centimeter ) . More than half of the patients had a past history of resection for another lung malignant neoplastic disease. Majority of tumours were adenocarcinomas. Nine patients had more than one tumour, which were considered to be synchronal, or metachronous primary lung malignant neoplastic diseases. The figure of investigations used was 1 in 20 tumours, 2 in 13 tumours, and 3 in 1 tumour. Eight patients ( 36 % ) had important cardiac or vascular disease that put them at high hazard for surgical resection. Limited pneumonic map was the prevailing determiner of medical inoperability in 6 patients ( 27 % ) . Four of these patients were on O therapy. Other comorbidities included nephritic disfunction, liver disfunction, and attendant malignances. Average CCI was 5 ±3, scope 3 to 15. Table 1 Table 1Patient and tumour features.The most common complications of cryoablation were pneumothoraces, minor haemoptysiss, and pleural gushs. Pneumothoraces were seen in 7 interventions ( 28 % ) . Pleural gushs were seen in 8 interventions ( 31 % ) . Minor haemoptysiss were seen in 6 patients ( 24 % ) . Chest tubing interpolation was required in one patient with pneumothorax. All other complications resolved with observation merely. The observation period ranged from 12-68 months, mean 29 ±19 months, average 23 months. Local tumour patterned advance after cryoablation was observed in one tumour ( 3 % ) which was a squamous cell carcinoma 1.6 centimeter in size. Local failure was recognized as progressive expansion of the ablated part at 8 months after cryoablation. At this clip, no other metastases were observed. The local recurrent tumour was re-cryoablated. Four months after re-cryoablation, the patient developed an upper respiratory infection, which lead to an acute aggravation of the implicit in idiopathic pneumonic fibrosis ( IPF ) . The patient later died of the acute aggravation. At this point, local control was maintained. Overall, the average local tumour progression-free interval was 69 ±2 months. Median local tumour progression-free interval was non reached ( Figure 1A ) . Figure 1 Figure 1Kaplan-Meier estimation curves of ( A ) local progression-free interval after cryoablation, ( B ) overall endurance after cryoablation, and ( C ) disease-free endurance after cryoablation.So far 3 patients ( 14 % ) have died. One patient was the patient described above. Another patient died of lung malignant neoplastic disease 68 months after cryoablation. This patient developed multiple systemic metastases whereas local control was maintained. This patient received chemotherapy one twelvemonth after cryoablation because distant metastases were detected. The staying one patient died of acute aggravation of IPF 18 months after cryoablation. In this instance, the acute aggravation of IPF occurred instantly after chemotherapy for attendant liver malignant neoplastic disease, and was non considered to be straight associated with lung cryoablation. There are 2 patients who have received chemotherapy and are alive. One patient developed multiple lung metastasis 48 months after cryo ablation and have received systemic therapy with gefitinib. Local control was maintained in this patient. The other patient developed multiple systemic metastases 4 months after cryoablation. Local control was maintained. This patient received systemic chemotherapy after sensing of distant metastases. The overall 2- and 3-year endurances were 88 % and 88 % , severally. Mean overall endurance was 62 ±4 months. Median overall endurance was 68 months ( Figure 1B ) . Five patients are alive with lung malignant neoplastic disease. The disease-free 2- and 3-year endurances were 78 % and 67 % , severally. Average disease-free endurance was 46 ±6 months. Median disease-free endurance was non reached ( Figure 1C ) . The forms of returns other than local return were as follows: Recurrence merely in the ipsilateral thorax was seen in 1 patient, which was lung metastases. Needle-tract airings or pleural returns have non been detected so far in any of the patients. Distant metastases were seen in 5 patients. These included metastases to contralateral thoraces, lumbar vertebra, ribs, and encephalon. Treatments for these patients included chemotherapy, radiation, and gamma-knife. Pneumonic map was evaluated in 16 patients ( 18 interventions ) before and 3 to 6 months after cryoablation. There were no important differences before and after cryoablation in critical capacity ( 2.72 ±0.82 L versus 2.64 ±0.74 L, P = 0.19 ) , per centum of predicted critical capacity ( 93 ±23 % versus 90 ±21, P = 0.11 ) , forced expiratory volume in 1 2nd ( 1.81 ±0.53 L versus 1.77 ±0.50 L, P = 0.14 ) ( Figure 2 ) , and per centum of forced expiratory volume in 1 2nd ( 70 ±11 % versus 70 ±12 % , P = 0.95 ) . Figure 2 Figure 2Individual alterations in forced expiratory volume in 1 2nd, and the mean  ± standard divergences before and after cryoablation.Travel to:DiscussionThere is roll uping grounds that RFA is a safe and executable intervention option for the intervention of inoperable phase I NSCLC. There is one study in which the consequences of cryoablation for phase I lung malignant neoplastic disease is included among the consequences of RFA and sublobar resections [ 10 ] . But to our cognition, this is the first study which specifically focuses on cryoablation in patients with medically inoperable phase I NSCLC. In the present survey, cryoablation was done safely in all patients. Reduction in pneumonic map after cryoablation was besides minimum in this survey, although the pneumonic map trial was done largely in patients with comparatively good pneumonic maps who could adequately execute the trial. The incidences of the most common complications, which were pneumothoraces, and pleural gush s, were comparable to those antecedently reported for RFA [ 5 ] , [ 6 ] , [ 12 ] , [ 13 ] , [ 14 ] . The reported local control rates for RFA intervention of inoperable phase I NSCLC ranged from 58 to 69 % [ 5 ] , [ 6 ] , [ 12 ] , [ 13 ] , [ 14 ] . The local control rate was somewhat higher in the present survey ( 97 % ) , presumptively because in our survey the tumours were 3 centimeter or less, really largely 2 centimeter or less, whereas old RFA surveies included tumours which were 4 centimeter or less. As for the one patient with local return, we speculate that the primary cause of local patterned advance was deficient border of extirpation. Although 2 investigations were used in this instance, it was hard to define the relationship between the border of extirpation and the border of the tumour on CT because of the implicit in IPF. We consider that farther accretion of experience is necessary to better intervention outcomes in such instances. The overall and disease-free endurance at 3 old ages were better than that antecedently reported for RFA [ 5 ] , 88 % and 67 % versus 47 % and 39 % , severally. This was besides presumptively because in our survey the tumours were 3 centimeter or less, whereas the old RFA survey included tumours which were 3-4 centimeter. In our survey, there were 6 patients with disease patterned advance other than local return, but the figure of patients was excessively little to measure if there is any characteristic form of disease patterned advance after lung malignant neoplastic disease cryoablation. Determination of medical inoperability is critically of import and should be assessed by an interdisciplinary squad. A patient should non be judged as inoperable by one factor entirely, such as hapless pneumonic map. Therefore the appraisal of medical operability requires a comprehensive rating of multiple factors in the patient. To this terminal, the group of patients in the present survey all had important associated comorbidities, with CCIs of & A ; gt ; = 3. This mark has been validated in surgically resected patients with lung malignant neoplastic disease [ 15 ] , [ 16 ] . In these studies, multivariate analysis showed that a CCI & A ; gt ; = 3 was a important prognostic factor of increased hazard of major complications. In the current survey, the patients who underwent cryoablation were aged ( average age, 72 old ages ) , had important comorbidities ( average CCI, 5 ) , and hence, were considered to stand for a bad population for surgery. Although farther followup is needed, so far merely one patient in this survey has died of lung malignant neoplastic disease, and other 2 patients have died of their comorbidities. This consequence suggests that minimally invasive intervention options such as cryoablation may really be appropriate for patients with significant comorbidities. In footings of efficaciousness, there is grounds to propose that cryoablation may ensue in improved local control in comparing to RFA in nephritic tumours [ 17 ] , but to our cognition there are no surveies comparing the two modes in lung tumours. Since this is a retrospective, experimental survey with a comparatively short followup in a limited figure of extremely selected patients subjected to multiple prejudices, farther surveies are necessary to more suitably address the results of cryoablation in comparing to RFA for early phase lung malignant neoplastic disease. SBRT is besides germinating to be a promising intervention option for early phase lung malignant neoplastic disease, with singular betterments in efficaciousness and safety. The indicants for SBRT and ablative processs are expected to be really similar, and farther surveies are necessary to define the strengths and failings of each of these modes, which may be complementary instead than reciprocally sole. Travel to:FootnotesCompeting Interests: The writers have declared that no viing involvements exist. Support: No external support was received for this survey. Travel to: